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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク 3-Indolepropionic acid ： ウィキペディア英語版 3-Indolepropionic acid 3-Indolepropionic acid (IPA), or indole-3-propionic acid, is a potent neuroprotective antioxidant and plant auxin that is being studied for therapeutic use in Alzheimer's disease.〔〔〔 It is endogenously produced within the human microbiome and detectable in humans only when the bacteria ''Clostridium sporogenes'' is present in the gastrointestinal tract.〔 (IPA metabolism diagram )〕 In individuals who lack ''C. sporogenes'' colonization, IPA is not detectable in the blood.〔〔 In order to synthesize IPA, ''C. sporogenes'' metabolizes tryptophan into indole and then subsequently 3-indolepropionic acid.〔 IPA is an even more potent scavenger of hydroxyl radicals than melatonin.〔〔 Similar to melatonin but unlike other antioxidants, it scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds. ''C. sporogenes'' is the only bacteria known to synthesize 3-indolepropionic acid ''in vivo'' at levels which are subsequently detectable in the blood stream of the host.〔 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「3-Indolepropionic acid」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.